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Methyl Charge+™ GF V

Methyl Charge+™
SKU Content Price  
Q1148 50 ml $30.00 Add To Cart
Methyl Charge+™ is a promethylation liposomal formula that includes vitamins B2, methyl-B12, trimethylglycine (TMG or betaine), B6 and folinic acid. Methyl Charge+TM represents a second generation methylation formulation, focusing on the catalytic activity of methyltranferases, a large class of important enzymes that broadly catalyze the transfer of methyl groups and thus modify DNA and gene expression. First generation methylation supplements focused solely on raising 5-MTHF (L-5- methyltetrahydrofolate), the naturally-occurring, active form of folic acid, to counter methylation issues arising from variations in the MTHFR gene (methylenetetrahydrofolate reductase). While this new formulation can be a stand-alone supplement to safely increase methylation dynamics in hypomethylators, it was originally developed to pair with our NAD+ GoldTM product. Methylation is critical to detoxification, glutathione regeneration1, and DNA repair, but early approaches to methylation ignored the vital connection of methylation cycles to the NAD+ cycle (see image below). In fact, supplementation with any compounds in the vitamin B3 family was intentionally avoided, as these NAD+ precursors were thought at the time to act as “methyl sponges”. Unfortunately, imbalanced supplementation with only pro-methylation compounds often yielded short-term benefits which gave way to a “crash” that is now understood to be mitochondrial dysfunction downstream of NAD+ deficiency.2
Supplement Facts
Supplement Facts
Serv. Size: 1 mL (2 Pumps)
Serv. Per Container: 50
Amount per Serving   %Daily Value
Riboflavin (as Riboflavin-5-Phosphate)10mg769%
Vitamin B-6 (as Pyridoxine HCI)1mg59%
Folate (as Calcium Folinate)850mcg DFE213%
Vitamin B-12 (as Methylcobalamin)500mcg20833%
Trimethylglycine (betaine)75mg**
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If pregnant, consult a physician before use.
** Daily Value (DV) not established
Other Ingredients: Water, Glycerin, Ethanol, Vitamin E (as Tocofersolan and Natural Mixed Tocopherols), Phospholipids (from purified sunflower seed lecithin), EDTA (as preservative), Natural Citrus Oils, Cinnamon Bark Oil, Natural Flavoring

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