The Aduco office will be closed on December 24–25 and December 31–January 1.

The Aduco office will be closed on December 24–25 and December 31–January 1. Orders placed during this time ship the next business day.

Free standard shipping and returns on all orders

Free standard shipping on all orders over $400.

Bi-Est+ Pro

Topical Replenishing Serum is a nanoemulsified, topical serum providing 1 mg of bioidentical estriol (E3) and 0.25 mg of bioidentical estradiol (E2) per serving.

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    • Topical Replenishing Serum

      The estriol and estradiol used to make up this formula originate from diosgenin, a phytosteroid extracted from soy. Bi-Est+ is delivered using proprietary lipid nanoparticle technology for enhanced absorption compared to conventional creams.*

      Patent-pending Quicksilver Delivery Systems® improve upon liposomal and emulsification technology with smaller, more stable particles made from the highest grade ingredients available.* This nanoformulated BI-EST Topical Replenishing Serum delivers fast and enhanced absorption of Estriol and Estradiol bypassing liver metabolism for optimal effects.*

    Topical Replenishing Serum

    The estriol and estradiol used to make up this formula originate from diosgenin, a phytosteroid extracted from soy. Bi-Est+ is delivered using proprietary lipid nanoparticle technology for enhanced absorption compared to conventional creams.*

    Patent-pending Quicksilver Delivery Systems® improve upon liposomal and emulsification technology with smaller, more stable particles made from the highest grade ingredients available.* This nanoformulated BI-EST Topical Replenishing Serum delivers fast and enhanced absorption of Estriol and Estradiol bypassing liver metabolism for optimal effects.*